|
Clinical History: 64 year-old male
with history of severe non ischemic cardiomyopathy, who received a orthotopic
heart transplant.
Histology: H&E section (Figure
A) of the myocardial tissue shows foci of perivascular mononuclear
cell infiltration with some associated myocardial damage consistent with
moderate acute cellular rejection (grade 2R) (ISHLT 1990 Grade 3A). Special immunohistochemistry
staining for CD3 and CD68 (Figure B and Figure C) show a
predominant population of T cells and macrophages. Special stating for CD20 shows
only a few
scattered B cells (Figure D). |
